Police rescue a turtle caught on fishing line, and it's up to Dr. Ross to unhook him; Dr. Blue waits for test results after performing dental surgery on a loveable dachshund; Dr. Lavigne gives a stray cat first-class treatment.
Dr. Lavigne does a not-so-routine surgery on a hermaphrodite dog that's both male and female; a bearded dragon battles a skin disease that Dr. Ross must treat before it causes serious problems; Dr. Blue manages work and a big family move.
Birds of prey at the Renaissance Faire are in need of the West Nile vaccine; Piper the peppy dachshund is not so peppy; Dr. Lavigne performs surgery; Dr. Ross helps Tesla the tortoise with a fractured beak.
Dr. Lavigne performs a doggy nose job to help a pug with bad breathing problems; Dr. Blue urgently treats Hardtime, a dog who's facing hard times battling heart disease; an opossum with a traumatic injury needs Dr. Ross's help.
A chicken is rushed to Dr. Ross after being attacked by a coyote; when a Great Dane mix has a seizure, Dr. Lavigne uncovers multiple issues; a surprise serenade at the clinic musically inspires Dr. Blue.
Follow veterinarians Dr. Diarra Blue, Dr. Aubrey Ross and Dr. Michael Lavigne, who recently moved to Houston to open a full-service veterinarian hospital and animal shelter together. The series captures the doctors' lives as they juggle running a new business while managing their family life filled with spouses, parents, in-laws, children, pets and friends, as well as their intense moments saving the lives of animals at their clinic.