Is there a theory that will encompass everything in the known universe? Inflation theory, quantum mechanics, string theory.
Are black holes real? Ultraluminous quasars and supermassive black holes, wormholes, and singularities.
What is the destiny of the universe? Dark matter, WIMPS, MACHOS, neutrinos.
What is the universe and everything in it made of? The creation of matter, the building up of elements in stars.